What makes our creams the best?
We use the most advanced bases available when compounding. The base is what we add the drug to to formulate a cream so that it can be easily applied to the skin. It is important that this base allows the drugs to enter the skin and not irritate it at the same time. Fortunately the bases we use do exactly this.
The bases we use belong to two families, the lipoderm bases and the versabase bases. The Lipoderm bases have been extensively studied and are proven to deliver up to four drugs simultaneously through the human skin. The reason Lipoderm is able to deliver up to four drugs at once is due to an added component that helps to push the drug through the skin.
The fact that Lipoderm can deliver four drugs at once has additional benefits. Because a transdermal dosage form has a more direct path to the bloodstream, the active ingredients can be administered at lower concentrations than the same medication in pill form, meaning you need less of the active drug to have the same effect.
Lipoderm is an elegant alternative to traditional pluronic lecithin organogels (PLO) and contains a proprietary liposomal component that increase the permeation of a variety of actives. Its touch and feel is smooth and creamy, unlike the tacky feel of PLOs. Lipoderm is a stable base that does not separate upon refrigeration and has great resiliency in the presence of ionic substances.
Lipoderm ActiveMax has the benefits of original Lipoderm with an added stabilizing system to provide resiliency in the presence of high salt loads. How do you know when/if you need Lipoderm ActiveMax? If you are using over 20% actives in a formula and experiencing separation or liquefaction problems, than using activemax can help overcome such issues.
Anhydrous Lipoderm utilizes similar technology to the well-studied and popular base, Lipoderm, and is an anhydrous version for actives that are unstable in water. It is also free of gluten, casein, egg, wheat-germ, paraben, butylated hydroxytoluene (BHT) and soy. This base utilizes rapeseed-based phospholipids, and may provide a better alternative for autistic patients than traditional Lipoderm. It also has a neutral odor and silky feel
Lipoderm High Molecular Weight, the latest in transdermal technology, is focused on the delivery of large molecular weight proteins. Lipoderm HMW does not contain lecithin, phospholipids or eggs, and could be an appropriate choice for autistic patients. This base has a low resiliency for salt forms of drugs, which cause the base to break.
The other bases we typically use belong to the versabase family. These bases stimulate the natural moisturizing barrier of the skin, providing smooth, non-irritating application. Available in five different applications (cream, gel, lotion, foam and shampoo), these topical bases are highly moisturizing, absorb quickly and have good spreadability with a silky touch
VersaBase Cream is an elegant, yet extremely durable, cosmetic cream. It simulates the natural moisturizing barrier of the skin through its emulsion system, can be used for a variety of pharmaceutical and cosmetic applications and is great for topical hormone replacement therapy.
VersaBase Gel is a versatile topical gel base that demonstrates excellent resiliency to low pH (2-7.5) and good compatibility with polar solvents, while maintaining a pleasant, silky feel. It can be used as a rheology modifier (thickener) or to make surfactant-free “gel creams.”
VersaBase Lotion is an elegant yet durable lotion base that is noncomedogenic, hypoallergenic, oil free, paraben-free and petrolatumfree. Its low viscosity emulsion system is highly moisturizing, absorbs quickly and has good spreadability with a silky soft touch. This versatile lotion can be used on the face, body and vaginally. VersaBase Lotion is appropriate for pharmaceutical and cosmetic applications. For patients who prefer a thinner emulsion for HRT, VersaBase Lotion is an option as well.
VersaBase Foam is made using the latest natural surfactant technology in order to be gentle on the skin. It is a solution that requires a foam dispenser to create the foam. VersaBase Foam base may be used at lower concentrations when desiring to leave on the skin (without washing off), as it provides great moisturizing ability. And, it may be used at up to a 100 percent concentration as a cleanser – usual ranges for this use are 50 to 100 percent.
VersaBase Shampoo has Natural Surfactants! Sodium lauryl sulfate (SLS)-free and paraben-free! VersaBase Shampoo is a mixture of different natural surfactants derived from corn and olives, which may be used both for pharmaceutical and cosmetic purposes, as well as in liquid soap formulas. The combination of olive and corn surfactants promotes better cleaning power and makes the formula less irritating. VersaBase Shampoo contains hydrating substances that help hair to be more malleable as well. It is appropriate for all types of hair, including color-treated hair. Also ideal for veterinary formulations.